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EMIT II Plus 6-Acetylmorphine Assay

Accurately screen for heroin use

EMIT II Plus 6-Acetylmorphine Assay Performance

 Assay Principle  Homogeneous Enzyme Multiplied Immonoassay (EMIT)
 Cut-off  10 ng/mL
 Assay range  0-20 ng/mL
 Sample  Urine  
 Reagent Stability  Unopened until expiration date; Opened working reagent, 4 weeks
 Calibration Frequency  Based on control results

Qualitative Precision (mA/min)

LevelMeanRepeatabilityWithin-Lab
(ng/mL)SD%CVSD%CV
Control 17.5 ng/mL5581.50.371.3
Cut-off10.0 ng/mL5911.70.36.51.1
Control 212.5 ng/mL6221.70.361

Semi-quantitative Precision (ng/mL)

LevelMeanRepeatabilityWithin-Lab
(ng/mL)SD%CVSD%CV
Control 17.5 ng/mL8.70.121.40.435.1
Cut-off10.0 ng/mL11.30.141.50.484.2
Control 212.5 ng/mL14.20.161.10.53.5
lg

Assay Specificity

Concentrations of compounds that produce negative results vs. the 10 ng/mL cut-off

Compounds Concentration Tested(ng/mL)
Buprenorphine1,000,000
Codeine500,000
Dextromethorphan100,000
Dihydrocodeine500,000
Heroin80
Hydrocodone300,000
Hydromorphone100,000
Imipramine200,000
Levorphanol100,000
Meperidine800,000
Morphine100,000
Morphine-3-Glucuronide600,000
Morphine-6-Glucuronide600,000
Nalorphine100,000
Naloxone300,000
Naltrexone300,000
Norcodeine600,000
Normophine100,000
Oxycodoen400,000
Oxymorphone100,000

Ordering information

The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens organization for further details.

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