The first clinical reader study to feature PRIME Technology* was carried out in Dortmund, Germany, and proved that images acquired with PRIME were of the same quality to those acquired with conventional grid based mammography.
More recently, Dr. Lisbet Brønsro Larsen of OUH Odense Universitetshospital Svendborg Sygehus, Odense, Denmark, presented the results of her new study investigating PRIME Technology in mammography screening at the ECR 2015 in Vienna, Austria.
The study of the screening program in the Region of Southern Denmark used Mammomat Inspiration systems that were upgraded with PRIME Technology. Recall rates, breast cancer detection rates and specificity were monitored over the five months following the upgrade and compared to the results of the twelve months prior to this.
22,117 women were examined using PRIME Technology in this five-month period, while the previous 12 months had seen 50,071 women screened using conventional grid-based mammography. Importantly, no significant differences were found in the recall rate, breast cancer detection rate or specificity between the two groups, in spite of the up to 30% reduction in dose** for the group examined with PRIME Technology.
This demonstrates that PRIME technology is not only able to reduce dose without compromising image quality, but also without reducing diagnostic accuracy. Given that mammography screening requires the examination of healthy women, this is a great step forward – and one that will enable thousands of women to reduce their exposure in the future.
*Mammomat Inspiration Prime is not commercially available in all countries. Due regulatory reasons its future availability cannot be guaranteed. Please contact your local Siemens organization for further information.
**Compared to grid-based acquisition with Mammomat Inspiration, depending on breast thickness